S.Africa’s Mandela admitted to hospital for tests












JOHANNESBURG (Reuters) – Former South African president Nelson Mandela was admitted to hospital on Saturday for medical tests, although the government said there was no cause for alarm.


A statement from President Jacob Zuma‘s office gave no details of the condition of the 94-year-old anti-apartheid leader.












Former President Mandela will receive medical attention from time to time which is consistent with his age,” the statement said.


President Zuma assures all that Madiba is doing well and there is no cause for alarm,” it added, referring to Mandela by his clan name.


Mandela, who became South Africa‘s first black president after the country’s first all-race elections in 1994, was admitted to hospital in February because of abdominal pain but released the following day after a keyhole examination showed there was nothing seriously wrong with him.


He has since spent most of his time in his ancestral home in Qunu, a village in the impoverished Eastern Cape province.


His frail health prevents him from making any public appearances in South Africa, although in the last few months he has continued to receive high-profile visitors, including former U.S. President Bill Clinton.


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Storm that killed 600 threatens Philippines again


NEW BATAAN, Philippines (AP) — A typhoon that had left the Philippines after killing nearly 600 people and leaving hundreds missing in the south has made a U-turn and is now threatening the country's northwest, officials said Saturday.


The weather bureau raised storm warnings over parts of the main northern island of Luzon after Typhoon Bopha veered northeast. There was a strong possibility the disastrous storm would make a second landfall Sunday, but it might also make a loop and remain in the South China Sea, forecasters said. In either case, it was moving close to shore and disaster officials warned of heavy rains and winds and possible landslides in the mountainous region.


Another calamity in the north would stretch recovery efforts thin. Most government resources, including army and police, are currently focused on the south, where Bopha hit Tuesday before moving west into the South China Sea.


With many survivors still in shock, soldiers, police and outside volunteers formed most of the teams searching for bodies or signs of life under tons of fallen trees and boulders swept down from steep hills surrounding the worst-hit town of New Bataan, municipal spokesman Marlon Esperanza said.


"We are having a hard time finding guides," he told The Associated Press. "Entire families were killed and the survivors ... appear dazed. They can't move."


He said the rocks, mud, tree trunks and other rubble that litter the town have destroyed landmarks, making it doubly difficult to search places where houses once stood.


On Friday, bodies found jammed under fallen trees that could not be retrieved were marked with makeshift flags made of torn cloth so they could be easily spotted by properly equipped teams.


Authorities decided to bury unidentified bodies in a common grave after forensic officials process them for future identification by relatives, Esperanza said.


The town's damaged public market has been converted into a temporary funeral parlor. A few residents milled around two dozen white wooden coffins, some containing unidentified remains.


One resident, Jing Maniquiz, 37, said she rushed home from Manila for the wake of two of her sisters, but could not bring herself to visit the place where her home once stood in Andap village. Her parents, a brother and nephew are missing.


"I don't want to see it," she said tearfully. "I can't accept that in just an instant I lost my mother, my father, my brother."


She said that at the height of the typhoon, her mother was able to send her a text message saying trees were falling on their house and its roof had been blown away.


Maniquiz said her family sought refuge at a nearby health center, but that was destroyed and they and dozens of others were swept away by the raging waters.


"We are not hopeful that they are still alive. We just want to find their bodies so that we will have closure," she said.


Mary Joy Adlawan, a 14-year-old high school student from the same village, was waiting for authorities to bury her 7-year-old niece.


Her parents, an elder sister, five nieces and a nephew are missing.


"I don't know what to do," she said as she fixed some flowers on the coffin.


Esperanza said heavy equipment, search dogs and chain saws were brought by volunteers from as far away as the capital, Manila, about 950 kilometers (590 miles) to the north.


Nearly 400,000 people, mostly from Compostela Valley and nearby Davao Oriental provinces, have lost their homes and are crowded inside evacuation centers or staying with relatives.


The typhoon plowed through the main southern island of Mindanao, crossed the central Philippines and lingered over the South China Sea for the past two days. It made a U-turn Saturday and is now threatening the northwestern Ilocos region.


President Benigno Aquino III, after visiting the disaster zone, declared a state of national calamity late Friday to speed up rescue and rehabilitation, control prices of basic commodities in typhoon-affected areas and allow the quick release of emergency funds.


In Bangkok, Thailand, U.N. humanitarian chief Valerie Amos said the Philippines had appealed for international aid. She said many countries have already provided assistance, but did not specify the amounts.


Officials say 276 people were killed in Compostela Valley, including 155 in New Bataan, and 277 in Davao Oriental. About 40 people died elsewhere and nearly 600 are still missing, 411 from New Bataan alone.


Davao Oriental Gov. Corazon Malanyaon told the AP that clean water and shelter were the biggest problem in three towns facing the Pacific Ocean. She said she imposed a curfew there and ordered police to guard stores and shops to stop looting.


The Philippines is also counting economic losses. Banana growers reported that 14,000 hectares (34,600 acres) of export banana plantations, equal to 18 percent of the total in Mindanao, were destroyed. The Philippines is the world's third-largest banana producer and exporter, supplying international brands such as Dole, Chiquita and Del Monte.


Stephen Antig, executive director of the Pilipino Banana Growers and Exporters Association, said losses were estimated at 12 billion pesos ($300 million), including 8 billion pesos ($200 million) in damaged fruits that had been ready for harvest, and the rest for the cost of rehabilitating farms, which will take about a year.


At the Vatican, Pope Benedict XVI expressed closeness to the people hit by the typhoon. "I pray for the victims, for their families and for the many homeless," the pontiff said Saturday, addressing pilgrims and tourists from his studio window overlooking St. Peter's Square.


___


Associated Press writers Oliver Teves and Hrvoje Hranjski in Manila, Francisco Rosario in Bangkok, Thailand, and Frances D'Emilio in Rome contributed to this report.


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Ghana election, test of democratic reputation












ACCRA, Ghana (AP) — Voters in Ghana were selecting their next president and a 275-seat parliament in elections Friday, solidifying the West African nation‘s reputation as a beacon of democracy in the region.


Some 14 million people are expected to turn out. President John Dramani Mahama, in office for only five months, is running against seven contenders. A former vice president, Mahama became president in July after the unexpected death of former President John Atta Mills. The 54-year-old is also a former minister and parliamentarian and has written an acclaimed biography, “My First Coup d’Etat.”












His main challenger is Nana Akufo-Addo, a former foreign minister and the son of one of Ghana’s previous presidents. The contender lost the 2008 election to Mills by less than 1 percent. Both men are trying to make the case that they will use the nation’s newfound oil wealth to help the poor.


Ghana, a nation of 25 million, is one of the few established democracies in the region as well as the fastest-growing economy. But a deep divide still exists between those benefiting from the country’s oil, cocoa and mineral wealth and those left behind financially.


In an interview on the eve of the vote, Akufo-Addo told The Associated Press that the first thing he will do if elected is begin working on providing free high school education for all. “It’s a matter of great concern to me,” he said, adding that he plans to use the nation’s oil wealth to educate the population, industrialize the economy and create better jobs for Ghanaians.


Policy-oriented and intellectual, Akufo-Addo is favored by the young and urbanized voters. He was educated in England and comes from a privileged family. The ruling party has depicted him as elitist, which Akufo-Addo calls “a little PR construct.”


“The idea that merely because you are born into privilege that automatically means you are against the welfare of the ordinary people, that’s nonsense,” he said.


Ghana had one of the fastest growing economies in the world in 2011. Allegations of corruption against the ruling party are rife.


Akufo-Addo said that if elected, he would not be able to weed out corruption in the government overnight.


“It’s a long fight,” he said. “But we build the institutions that can fight it.”


He said that in 30 years in politics he has never been accused of corruption.


Many analysts believe Mahama and Akufo-Addo are neck-and-neck.


Results are expected to be announced by Sunday, but could be delayed. If no one wins an absolute majority, a second round of voting will be held on December 28.


All candidates have signed a peace pact and have promised to accept the results of Friday’s poll.


Ghana, a nation of 25 million, has previously held five transparent elections in a row. Nearby Mali, which was also considered a model democracy, was plunged into chaos this March following a military coup.


__


Associated Press writer Francis Kokutse contributed to this report from Accra, Ghana.


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Crowdfunding websites clamor for clearer regulation












LONDON (Reuters) – A new breed of internet-based financiers are calling for action to end regulatory uncertainty they say is preventing them from getting money to the small and medium-sized businesses that need it.


The so-called crowdfunding sector raises cash from members of the public to fund lending and investment. Regulators, however, have proved resistant to pleas for adjustments to rules that are tailored to more traditional markets.












“Operators of these platforms find it difficult to launch and flourish because existing EU and UK regulation does not fit the new models,” operators within the sector said in an open letter to EU and UK policymakers on Friday.


The plea coincides with a summit to discuss proposals for regulating a market that has developed in reaction to reduced bank lending to small and medium-sized enterprises because of tougher capital rules and greater regulatory scrutiny.


A host of alternative financing models have cropped up online, many allowing individuals to lend to, or invest in, companies with sums from as little as 10 pounds ($ 16). Massolution, a research and advisory firm specializing in the sector, says that 1.2 billion euros ($ 1.6 billion) was raised globally from crowdfunding last year.


Though some crowdfunding websites have tried to fit their operations within the existing regulatory framework, most remain largely outside it.


Part of the problem in drawing up appropriate regulation is the wide range of activities involved. Some offer debt, some equity, while others seek donations for charity or funding for creative projects in return for some non-financial reward.


With little or no expected returns from the latter, the main regulatory focus would be on equity crowdfunding and peer-to-peer lending.


As well as making sure that individuals are aware of the inherent risk involved with putting money in start-ups, the industry wants to avoid the risk of scams by ensuring that platforms vet businesses adequately.


LOST IN THE CROWD


Britain’s Financial Services Authority (FSA) warned in August that inexperienced investors should be aware of the risks in crowdfunding websites. A few days later United States securities regulators put crowdfunding at the top of their annual investment scams list.


Views differ about how to tackle these risks without stifling an increasingly important source of funding, and the matter is complicated by the varying rules already in place in different countries across Europe.


Measures taken by Seedrs, the only crowdfunding website to have received FSA approval, include requiring investors to pass a test to show that they understand the risks.


“It is hard to come up with a whole securities regulation; sometimes it does have to be a bit incremental and adaptive,” Seedrs founder Jeff Lynn said. “There is no question at all this is going to be a space that will continue to move.”


Some would like the operation of such platforms to be a distinct regulated activity, but others argue for smaller steps, such as a cap on the sums that people can invest or lend.


The British government, keen to improve the flow of finance to small businesses to boost the sluggish economy, has set up a working group to look at all aspects of policy on such sites.


The FSA said that it considers authorization of crowdfunding schemes case by case. The European Commission, meanwhile, is considered as so far having had a largely observational role.


Though the introduction of a separate regulated activity could still be some way off, the co-founder of peer-to-peer site Zopa, Simon Deane-Johns, believes that increased engagement with governments and regulators shows that things are moving in the right direction.


“Over the next year or two it should become progressively easier to set up a platform,” he said, “possibly through a combination of the FSA understanding more readily where things fit within the current regime and balancing that with some self-regulation.”


(Editing by Alexander Smith and David Goodman)


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Jackson’s Hobbit: the journey begins












WELLINGTON (Reuters) – Film maker Peter Jackson wants to scare children with his latest movie – and perhaps even a few grown ups.


The first of the Hobbit movie trilogy – “The Hobbit: An Unexpected Journey” – is about to hit theatres, and Jackson says he’s tried to hold true to its roots as a children’s fantasy story, with scary bits.












“If they’re scared of the trolls great, if they’re scared of the goblins great, they know there are no goblins, they know there are no trolls, it’s a safe kind of danger,” he says.


The film, produced by MGM and Time Warner Inc, is the fourth in the Oscar-winning Jackson’s blockbuster “Lord of the Rings” film franchise, based on the books of author J.R.R. Tolkien.


It follows the journey of hobbit Bilbo Baggins, reluctantly pushed into travelling with 13 dwarves to steal treasure from a dragon and regain their homeland. During his travels, he comes by the ring that he later passes onto kinsman Frodo Baggins, which was at the core of the “Rings” trilogy.


Jackson says he’s worked to keep distance between the Hobbit, published in 1937, and the much darker Lord of the Rings, which came out nearly 20 years later.


“The Lord of the Rings has an apocalyptic sort of heavy themic end-of-the world quality to it, which the Hobbit doesn’t, which is one of the delights of it,” he said.


POMPOUS AND SMALL MINDED


The pointy eared, hairy footed hobbit Bilbo is played by British actor Martin Freeman, who says he’s tried to make Bilbo his own creation, a character audiences can root for despite his initial pomposity and small mindedness.


“You have to be able to follow him for the duration of the film, but I wanted him to be open and changeable and ready to be surprised,” Freeman said.


A key scene is an encounter in a cave between Bilbo and the creature Gollum, reprised in full computer generated splendor by Andy Serkis with the distinctive throaty whisper.


“It was a very rich experience,” he said, adding that playing Gollum again was “an absolute thrill”.


Such is the affection for the creature, who calls the magic ring “Precious”, that a 13 meter (42 feet) sculpture of Gollum hangs in the airport terminal at Wellington, which regards itself as the spiritual home of the Tolkien films and terms itself the “Middle of Middle Earth”.


Returning actors from the Rings trilogy, many of whom have only passing mention in the book, were no less enthusiastic. Ian McKellen returns for a leading role as the wispy-haired, grey bearded wizard, Gandalf, while Cate Blanchett is the elven queen Galadriel and Elijah Wood appears as Frodo Baggins.


“You couldn’t not come back, you had to come back,” says Hugo Weaving, the leader of the elves, Elrond.


HOBBIT – A FRAUGHT JOURNEY


The Hobbit film journey has not been without its setbacks.


Metro-Goldwyn-Mayer, owners of the film rights to the Tolkien books, had financial woes, prompting original director Guillermo del Toro to pull out and Jackson, already script writer and executive producer, to step in.


A major labor dispute prompted threats to move production out of New Zealand, and was solved by changing labor laws, while Jackson suffered a perforated ulcer and underwent surgery, delaying the film still further.


Though only two films were planned originally, Jackson has tapped Tolkien’s appendices to the Rings to make it into three.


Audiences are also getting more visual bangs for their buck, with the movies filmed in 3D and at 48 frames per second (fps), double the industry standard.


This delivers clearer pictures, but opinion is divided, with some critics calling it cartoon-like and jarring.


Jackson says he wants to drag the iPad generation back into theatres and the romance, excitement and mystery they offer.


“It’s more realistic, it’s more immersive. I almost feel a responsibility as a film maker to try to do my part at encouraging people to come to the movies, to watch the film in a cinema,” he said.


The second film “The Hobbit: The Desolation of Smaug” will be released in December next year, with the third “The Hobbit: There and Back Again” is due in mid-July 2014.


(Reporting by Gyles Beckford, editing by Elaine Lies)


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Smokers celebrate as Wash. legalizes marijuana












SEATTLE (AP) — The crowds of happy people lighting joints under Seattle‘s Space Needle early Thursday morning with nary a police officer in sight bespoke the new reality: Marijuana is legal under Washington state law.


Hundreds gathered at Seattle Center for a New Year’s Eve-style countdown to 12 a.m., when the legalization measure passed by voters last month took effect. When the clock struck, they cheered and sparked up in unison.












A few dozen people gathered on a sidewalk outside the north Seattle headquarters of the annual Hempfest celebration and did the same, offering joints to reporters and blowing smoke into television news cameras.


“I feel like a kid in a candy store!” shouted Hempfest volunteer Darby Hageman. “It’s all becoming real now!”


Washington and Colorado became the first states to vote to decriminalize and regulate the possession of an ounce or less of marijuana by adults over 21. Both measures call for setting up state licensing schemes for pot growers, processors and retail stores. Colorado’s law is set to take effect by Jan. 5.


Technically, Washington’s new marijuana law still forbids smoking pot in public, which remains punishable by a fine, like drinking in public. But pot fans wanted a party, and Seattle police weren’t about to write them any tickets.


In another sweeping change for Washington, Gov. Chris Gregoire on Wednesday signed into law a measure that legalizes same-sex marriage. The state joins several others that allow gay and lesbian couples to wed.


The mood was festive in Seattle as dozens of gay and lesbian couples got in line to pick up marriage licenses at the King County auditor’s office early Thursday.


King County and Thurston County announced they would open their auditors’ offices shortly after midnight Wednesday to accommodate those who wanted to be among the first to get their licenses.


Kelly Middleton and her partner Amanda Dollente got in line at 4 p.m. Wednesday.


Hours later, as the line grew, volunteers distributed roses and a group of men and women serenaded the waiting line to the tune of “Chapel of Love.”


Because the state has a three-day waiting period, the earliest that weddings can take place is Sunday.


In dealing with marijuana, the Seattle Police Department told its 1,300 officers on Wednesday, just before legalization took hold, that until further notice they shall not issue citations for public marijuana use.


Officers will be advising people not to smoke in public, police spokesman Jonah Spangenthal-Lee wrote on the SPD Blotter. “The police department believes that, under state law, you may responsibly get baked, order some pizzas and enjoy a ‘Lord of the Rings’ marathon in the privacy of your own home, if you want to.”


He offered a catchy new directive referring to the film “The Big Lebowski,” popular with many marijuana fans: “The Dude abides, and says ‘take it inside!’”


“This is a big day because all our lives we’ve been living under the iron curtain of prohibition,” said Hempfest director Vivian McPeak. “The whole world sees that prohibition just took a body blow.”


Washington’s new law decriminalizes possession of up to an ounce for those over 21, but for now selling marijuana remains illegal. I-502 gives the state a year to come up with a system of state-licensed growers, processors and retail stores, with the marijuana taxed 25 percent at each stage. Analysts have estimated that a legal pot market could bring Washington hundreds of millions of dollars a year in new tax revenue for schools, health care and basic government functions.


But marijuana remains illegal under federal law. That means federal agents can still arrest people for it, and it’s banned from federal properties, including military bases and national parks.


The Justice Department has not said whether it will sue to try to block the regulatory schemes in Washington and Colorado from taking effect.


“The department’s responsibility to enforce the Controlled Substances Act remains unchanged,” said a statement issued Wednesday by the Seattle U.S. attorney’s office. “Neither states nor the executive branch can nullify a statute passed by Congress.”


The legal question is whether the establishment of a regulated marijuana market would “frustrate the purpose” of the federal pot prohibition, and many constitutional law scholars say it very likely would.


That leaves the political question of whether the administration wants to try to block the regulatory system, even though it would remain legal to possess up to an ounce of marijuana.


Alison Holcomb is the drug policy director of the American Civil Liberties Union of Washington and served as the campaign manager for New Approach Washington, which led the legalization drive. She said the voters clearly showed they’re done with marijuana prohibition.


“New Approach Washington sponsors and the ACLU look forward to working with state and federal officials and to ensure the law is fully and fairly implemented,” she said.


___


Johnson can be reached at https://twitter.com/GeneAPseattle


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Boehner: Obama insisting on 'my way or the highway'




House Speaker John Boehner today said no progress has been made in negotiations with President Obama, demonstrating the persistence of a bullheaded standoff between the two party leaders just 24 days before the fiscal cliff deadline.



"This isn't a progress report because there's no progress to report," Boehner, R-Ohio, told reporters at a news conference from the Capitol this morning. "When it comes to the fiscal cliff that's threatening our economy and threatening jobs, the White House has wasted another week."



The primary sticking point continues to be a disagreement over how to address tax cuts set to expire for taxpayers making above $250,000. The president insists rates on the wealthy must increase as part of an agreement, and so far Boehner has been adamant that any new revenue included in a deal must be created by closing tax loopholes and capping deductions.



"Raising taxes on small businesses is not going to help our economy and it's not going to help those seeking work," the speaker said. "I came out the day after the election to put revenues on the table to take a step towards the president to try to resolve this. When is he going to take a step towards us?"



Get more pure politics at ABCNews.com/Politics and a lighter take on the news at OTUSNews.com



Boehner said his phone call with Obama on Wednesday was not productive, and negotiations between White House officials and the speaker's top aides this week have not brought either side closer to an agreement.



"The phone call was pleasant but was just more of the same," Boehner said. "It's time for the president, if he's serious, to come back to us with a counteroffer."



Asked whether he could find a middle ground on increasing the top tax rates while simultaneously protecting small business, the speaker seemed to suggest a hint of flexibility on what has been a red line issue for Republicans up to this point.



"There are a lot of things that are possible to put the revenues that the president seeks on the table, but none of it's going to be possible [if] the president insists on his position, insists on 'my way or the highway,'" he said. "That's not the way to get to an agreement that I think is important for the American people and very important for our economy."



View ABC News' comprehensive coverage of the fiscal cliff talks.



Reports indicate that negotiations have narrowed to include only the speaker's top policy aides and senior White House officials - cutting the Senate and House Democrats out of the talks for now.



House Democratic Leader Nancy Pelosi declined to disclose when she last spoke with Obama, but she did have a photo taken with him at a White House holiday reception on Monday. Today, she expressed solidarity with her president.



"I don't necessarily talk about when and how many times I speak to the president, but I'm very satisfied with the communication that I have with the president," she said. "The president knows our views. He shares our values. We feel confident in any negotiation that he takes the lead in."



Boehner once again condemned the president's only formal offer on Nov. 29, which called for $1.6 trillion in new revenue over the next decade, presidential power over the debt limit, and about $400 billion in new stimulus spending, predicting it would be a recipe for "trillion dollar deficits for as far as the eye can see."



"The president has adopted a deliberate strategy to slow-walk our economy right to the edge of the fiscal cliff," Boehner said. "If the president doesn't agree with our proposal, I believe that he's got an obligation to families and small businesses to offer a plan of his own - a plan that can pass both chambers of the Congress. We're ready and eager to talk to the president about such a plan."



Boehner also derided the president's request for what the speaker describes as "an infinite increase in the debt limit, like forever."



As Obama and Boehner consider the options to devising a bipartisan package, congressional insiders say the pressure is on both leaders to find the right touch that will win over adequate support to pass in the House and Senate.



"The bigger issue is Boehner is on the hook to negotiate on good faith on a deal that we [House Democrats], the White House and Senate Democrats would ok that includes [increases to tax] rates," one senior House Democratic leadership aide said. "Hate to be in his position."


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South Africa military plane crashes in mountains












JOHANNESBURG (AP) — A South African military aircraft on an unknown mission to an area near the village where former President Nelson Mandela lives crashed in a mountain range, officials said Thursday. It was unclear whether there were any survivors.


The Douglas DC-3 Dakota, a twin-propeller aircraft, had taken off from Pretoria’s Waterkloof Air Force Base on Wednesday night, said Brig. Gen. Xolani Mabanga, a military spokesman. On Thursday morning, soldiers found the wreckage of the airplane in the Drakensberg mountains near Ladysmith in KwaZulu-Natal province, some 340 kilometers (210 miles) southeast of the air base, Mabanga said.












Mabanga said soldiers had been sent to the scene to look for survivors. Mabanga said he did not know what the mission of the aircraft was, though it had planned to land in Mthatha in the country’s Eastern Cape. Siphiwe Dlamini, a Defense Ministry spokesman, declined to immediately comment Thursday morning.


Mthatha is about 30 kilometers (17 miles) north of Qunu, the village where Mandela now lives after retiring from public life. South Africa‘s military remains largely responsible for the former president’s medical care. However, military officials declined to say whether those on board had any part in caring for Mandela.


In November, another South African military flight crash landed at Mthatha, sending several people to the hospital with injuries. However, at that time, the military denied that those on board had anything to do with Mandela’s care.


Mandela, 94, was imprisoned for nearly three decades for his fight against apartheid before becoming the nation’s president in the country’s first fully democratic vote in 1994.


___


Jon Gambrell can be reached at www.twitter.com/jongambrellAP .


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Latest James Bond movie breaks UK box office record












LONDON (Reuters) – “Skyfall“, the 23rd official James Bond movie, has become the most successful film in British box office history, earning 94.3 million pounds ($ 152 million), its producers said on Wednesday.


The tally, earned over 40 days, surpasses the previous record of 94.0 million pounds set by 2009 3D adventure film “Avatar” over its 11 month run in UK cinemas, although the figures do not take inflation into account.












Skyfall, which has been well received by critics, stars Daniel Craig in his third outing as 007, and is directed by Sam Mendes.


In it Bond and British spymaster M, played by Judi Dench, are pitted against technological wizard Silva (Javier Bardem) who is bent on revenge.


“We are very proud of this film and thank everybody, especially Daniel Craig and Sam Mendes, who have contributed to its success,” said co-producers Michael G. Wilson and Barbara Broccoli in a statement.


Globally, Skyfall has some way to go to match Avatar. It has earned $ 870 million in ticket sales around the world, according to movie tracking site Boxofficemojo.com, compared with Avatar’s record $ 2.8 billion.


According to the same website, Avatar’s adjusted box office total comes in at 14th in cinema history, with the 1939 classic “Gone With the Wind” in pole position.


(Reporting by Mike Collett-White, editing by Paul Casciato)


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Breast Cancer Vaccine a Reality for Women With HER-2 Negative Cancers












COMMENTARY | NeuVax, a breast cancer vaccine, is entering phase III trials. The drug’s manufacturer, Galena Biopharma, announced on Dec. 5, that it signed a distribution deal with TEVA Pharmaceuticals. TEVA will handle the global commercialization and distribution of the drug once it is out of trials. It is about time this is moving forward. We need to make progress toward ending this disease.


What is NeuVax?












A vaccine called NeuVax is close to being a reality for breast cancer patients. NeuVax is a vaccine, the first of its kind, to prevent breast cancer from recurring. A recurrence is when breast cancer returns to the same breast. If breast cancer appears in the other breast, it is not a recurrence but a new cancer.


Most women have a 15-20 percent chance of breast cancer recurring, even after a mastectomy. The implications of the vaccine are huge. It reduces the chance of breast cancer recurrence in women with node-positive, HER-2 negative breast cancers. About 75 percent of all breast cancer is HER-2 negative. The vaccine is given after the standard course of treatment is completed. It is not a replacement for radiation or chemotherapy. I would gladly try a vaccine over the currently available long-term recurrence preventions — all are hormone based and carry awful side effects.


Phase III trials


Unfortunately for me, there are no trials available in Arkansas. Even if there were, I am not eligible because my cancer is HER-2 positive, and I am thankfully, node-negative. This means that the cancer is not in my lymph system. Phase III trials are when the drug is actually tested in random settings on humans. This drug seems to be very promising. Right now, phase III trials are open in the United States and Canada. Israel will have at least four phase III trials opening soon. You can see if there are trials near you at the NeuVax website.


This vaccine has the potential to replace hormone therapies like tamoxifen and aromatase inhibitors. Both types of drugs have serious side effects. A vaccine, taken over the course of three years, reduces the time a patient needs to take medications and it helps to prevent recurrence. Hopefully the phase III trials go well and we get this vaccine available to breast cancer patients soon.


Lynda Altman was diagnosed with breast cancer in November 2011. She writes a series for Yahoo! Shine called “My Battle With Breast Cancer.”


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